Alprostadil is a synthetic form of prostaglandin E1 (PGE1), a naturally occurring hormone-like substance in the body. Chemically, it is a prostaglandin analog. Alprostadil is used therapeutically for various medical purposes, including the treatment of erectile dysfunction (ED), certain types of congenital heart defects, and peripheral vascular disease. In the treatment of ED, alprostadil works by relaxing smooth muscle tissue in the blood vessels of the penis, leading to increased blood flow and penile erection. It is available in different formulations for ED treatment, including intracavernosal injections, urethral suppositories, and topical creams or gels.
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