Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Gentamicin. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Gentamicin is an aminoglycoside antibiotic used to treat various bacterial infections. Structurally, it is composed of a mixture of related compounds. Gentamicin works by inhibiting bacterial protein synthesis, binding to the 30S ribosomal subunit and disrupting the formation of the initiation complex for protein synthesis. Administered through injection or topical application, gentamicin is effective against a wide range of Gram-negative bacteria, including certain strains resistant to other antibiotics.
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