Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Meropenem. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Meropenem is a broad-spectrum antibiotic belonging to the carbapenem class. It is widely used to treat severe bacterial infections, including intra-abdominal infections, pneumonia, and complicated skin and soft tissue infections. Structurally, it is a beta-lactam antibiotic, and its mechanism of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins.Administered intravenously, meropenem exhibits activity against a wide range of Gram-positive and Gram-negative bacteria, making it a valuable choice for empiric treatment in critically ill patients. Its broad spectrum and effectiveness against multidrug-resistant organisms contribute to its role in tackling serious infections.
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